http://www.freedomscientific.com/products/fs/jaws-product-page.asp

Powerful access to screen content
Get started today working with all your Microsoft and IBM Lotus짰 Symphony꽓 applications using JAWS짰, the world's most popular screen reader. Developed for computer users whose vision loss prevents them from seeing screen content, JAWS reads aloud what's on the PC screen.

Compatible with the most frequently-used workplace and classroom applications
JAWS enables you to work with Lotus Symphony, a suite of IBM짰 tools for word processing, spreadsheets, and presentation creation and with Lotus Notes짰 by IBM. JAWS also is compatible with Microsoft짰 Office Suite, MSN Messenger짰, Corel짰 WordPerfect, Adobe짰 Acrobat Reader, Internet Explorer꽓, Firefox꽓 - and many more applications that are used on a regular basis on the job and in school.
 
Unmatched braille support
With a refreshable braille display, JAWS also provides braille output in addition to, or instead of, speech. An array of versatile features and customizable options lets you tailor JAWS for your individual needs and preferences.

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